The protocol was signed as the final document at the two-day conference called "The Adriatic Euroregion - A Contribution to European Integration".
The event pooled representatives of governments and local authorities from Italy, Slovenia, Croatia, Bosnia-Herzegovina, Serbia-Montenegro, Albania and Greece.
According to the document, the Euroregion will work on strengthening stability and promoting viable development as well as on creating economic and social cohesion and integrating Adriatic countries into the European Union.
Next March, Istria County will organise the first meeting of the interim Adriatic Council which is expected to define the statute, organisation and models of financing the new region and establish the permanent Council.
The first chairman of this new region will be Istria County Prefect Ivan Jakovcic.
"To chair the Adriatic Euroregion is great honour and helps us to promote more strongly Istria," Jakovcic told Hina.
Croatian Ambassador to Italy, Drago Kraljevic, said the results of the Termoli conference presented a possibility for implementing cross-border cooperation and that the Euroregion was a part of Croatia's foreign policy, too.