The formed Bosnian Serb leader is charged with having committed genocide and crimes against humanity against Bosniaks and Croats during the war in Bosnia in 1992-1995.
Krajisnik's defence attorney, Briton Nicholas Stewart, said in his opening statement that the prosecution failed to provide sufficient evidence to back up the accusations against his client adding that he would prove his client's innocence and demand acquittal.
After the opening statement the defence called its first witness, a war-time president of the northern Bosnian municipality of Prnjavor, Nemanja Vasic.
The trial of Krajisnik (aged 60), who is also charged with having participated in a joint criminal enterprise of ethnic cleansing in parts of Bosnia aimed at annexing those parts to a Greater Serbia, commenced on 3 February 2004.