The case is about a city whose residents were continually tortured by an orchestrated campaign of sniping and mortar fire, prosecutor Alex Whiting said in his opening statement at the beginning of the trial.
General Milosevic was chief-of-staff and later commander of the Republika Srpska Army's Sarajevo-Romanija Corps.
He is charged with a sniping and mortar campaign to which the residents of Sarajevo were subjected from August 1994 to April 1995.
The Hague tribunal last year sentenced to life Milosevic's predecessor at the post of Sarajevo-Romanija Corps commander, General Stanislav Galic, for the terror campaign against the residents of Sarajevo.