FILTER
Prikaži samo sadržaje koji zadovoljavaju:
objavljeni u periodu:
na jeziku:
hrvatski engleski
sadrže pojam:

Croatian researchers find links between glycan changes and cardiovascular diseases

Author: Marija Šestan

ZAGREB, March 14 (Hina) - Researchers at the Genos Laboratory in Zagreb have found that glycans can serve as excellent biomarkers in establishing risks of cardiovascular diseases.

The study, conducted in cooperation with King's College London and the University of Edinburgh, included analysis of the health of 4,500 people.

The objective of the study was "to assess the role of a comprehensive panel of immunoglobulin (IgG) glycosylation traits on traditional risk factors for cardiovascular disease and on presence of subclinical atherosclerosis in addition to GlycA," according to an article published in Circulation Research of the American Heart Association.

The results show that the researchers have found "molecular pathways linking IgG to arterial lesion formation. Glycosylation traits are independently associated with subclinical atherosclerosis. One specific trait related to the sialylated N-glycan is negatively correlated with CVD risk, VLDL and triglyceride serum levels and presence of carotid plaque."

(Hina) ms

An unhandled error has occurred. Reload 🗙