Johansson said that only one percent of the profit was blocked, announcing a plan for the seizure of illegally gained money.
The commissioner, who took office at the beginning of this year, is also preparing new European plans for the fight against drug, weapons and people smuggling.
Our priorities are stronger police cooperation, information exchange and a stronger Europol mandate, Johansson said at a news conference after an informal meeting of EU home affairs ministers in Zagreb.
The chair of the meeting, Croatian Minister of the Interior Davor Bozinovic, said that citizens rightfully expected their governments to protect them.
Security is one of the main concerns of our citizens and we have the responsibility to find the right answers to those concerns, said Bozinovic.
The EU home affairs ministers discussed the fight against organised crime, terrorism and people smuggling and the protection of children on the Internet.
Also discussed were migrations, the fight against people smuggling rings and a new European pact on migration and asylum.
Johansson said that so far she had talked to 15 member-states about the pact, which is expected to replace the Dublin asylum system that collapsed under the 2015 migration wave.
The member-states have a constructive approach even though their starting positions are different, Johansson said, expressing the belief that a pact would be presented that would be acceptable to all member-states.
The ministers also discussed the situation in Libya and the Middle East where conflicts threaten to trigger and send a new wave of refugees towards Europe.
"I am confident that Europe is ready (to protect its borders). What needs to be worked on is a consensus among member-states and focus on real problems," said Bozinovic.
Johansson stressed that Europe should not just stand by and watch what was going on in its broader neighbourhood.
The EU must be more active and help find solutions in Libya and Iran. Cooperation with third countries is one of the most important things, she said.
The existing EU-Turkey agreement, which stopped the refugee wave from Syria, will continue to be in force for some time, Johansson said but she could not say what the new agreement with Ankara would be like.
Johansson also said that she would discuss the EU's new plan for assistance to Greece, the member country most exposed to migrant arrivals from the Middle East, with the new Greek minister for migrations on Tuesday.
Bozinovic said that there was a need for a European response and that an analysis of future measures currently focused on Greece.